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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11475 | GSK-J1 lithium salt | Histone Demethylase | |
GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B. | |||
T6847 | GSK-J1 | GSK J1 | Histone Demethylase |
GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases. |